
| Name | Radix ranunculus temate saponins | ||
| PubChem CID | / | ||
| Structure |
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2D
MOL
3D
MOL
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| Chineses Pinyin | MaoZhuaCao | ||
| Use Part | Root tuber | ||
| Flavor | Sweet; Pungent | ||
| Meridian Tropism | Liver; Lung | ||
| Species |
>Kingdom: Viridiplantae
-->Phylum: Streptophyta
-->Class: Equisetopsida
-->Order: Ranunculales
-->Family: Ranunculaceae
-->Genus: Ranunculus
-->Species: Ranunculus ternatus
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| Pair Name | Radix ranunculus temate saponins, Paclitaxel | |||
| Partner Name | Paclitaxel | |||
| Disease Info | [ICD-11: 2C73] | Ovarian cancer | Investigative | |
| Gene Regulation | Down-regulation | Expression | COL3A1 | hsa1281 |
| In Vitro Model | A2780 | Ovarian endometrioid adenocarcinoma | Homo sapiens (Human) | CVCL_0134 |
| OVCAR-3 | High grade ovarian serous adenocarcinoma | Homo sapiens (Human) | CVCL_0465 | |
| SK-OV-3 | Ovarian serous cystadenocarcinoma | Homo sapiens (Human) | CVCL_0532 | |
| In Vivo Model | A2780 cells (1×10⁶) were injected subcutaneously into the back of six-week-old BALB/c nu/nu female mice. | |||
| Result | Combination of Taxol and RRTS may be a novel treatment strategy for patients with TR ovarian cancer. | |||